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Complete Publication List at PubMed

Hippee CE, Klingelhutz A, Wu LStudent-led discussions of landmark discovery articles: a foothold in teaching primary virology literature. J Microbiol Biol Educ. 2024 Oct 23;:e0018424. doi: 10.1128/jmbe.00184-24. [Epub ahead of print] PubMed PMID: 39440924. 

Mishra T, Phillips S, Zhao Y, Wilms B, He C, Wu LEpitranscriptomic m(6)A modifications during reactivation of HIV-1 latency in CD4(+) T cells. mBio. 2024 Oct 7;:e0221424. doi: 10.1128/mbio.02214-24. [Epub ahead of print] PubMed PMID: 39373537.

Mishra T, Phillips S, Maldonado C, Stapleton JT, Wu LAntiretroviral Therapy Suppresses RNA N(6)-Methyladenosine Modification in Peripheral Blood Mononuclear Cells from HIV-1-Infected Individuals. AIDS Res Hum Retroviruses. 2024 Sep;40(9):511-520. doi: 10.1089/AID.2024.0003. Epub 2024 May 23. PubMed PMID: 38753726

Mishra T, Phillips S, Wu L. Method for the Enrichment of N(6)-Methyladenosine-Modified Cellular and HIV-1 RNA. Methods Mol Biol.2024;2807:195-208. doi: 10.1007/978-1-0716-3862-0_14. PubMed PMID: 38743230

Baek A, Lee GE, Golconda S, Rayhan A, Manganaris AA, Chen S, Tirumuru N, Yu H, Kim S, Kimmel C, Zablocki O, Sullivan MB, Addepalli B, Wu L, Kim S. (2024). Single-molecule epitranscriptomic analysis of full-length HIV-1 RNAs reveals functional roles of site-specific m(6)As. Nat Microbiol. 9(5):1340-1355. doi: 10.1038/s41564-024-01638-5. PMID: 38605174.

Phillips S, Mishra T, Huang S, Wu L. (2024). Functional Impacts of Epitranscriptomic m6A Modification on HIV-1 Infection. Viruses. 2024 Jan 16;16(1):127. doi: 10.3390/v16010127.PMID: 38257827.

Tang Y, Behrens RT, St Gelais C, Wu S, Vivekanandan S, Razin E, Fang P, Wu L, Sherer N, Musier-Forsyth K. Human lysyl-tRNA synthetase phosphorylation promotes HIV-1 proviral DNA transcription. Nucleic Acids Res. 2023 Dec 11;51(22):12111-12123. doi: 10.1093/nar/gkad941. PMID: 37933844.

Jiang ZH, Chen QY, Jia HH, Wang XY, Zhang LJ, Huang XQ, Harrison TJ, Jackson JB, Wu L, Fang ZL. Low host immune pressure may be associated with the development of hepatocellular carcinoma: a longitudinal analysis of complete genomes of the HBV 1762T, 1764A mutant. Front Oncol. 2023;13:1214423. doi: 10.3389/fonc.2023.1214423. eCollection 2023. PMID 37681020.

Espada CE, Sari L, Cahill MP, Yang H, Phillips S, Martinez N, Kenney AD, Yount JS, Xiong Y, Lin MM, & Wu L. (2023). SAMHD1 impairs type I interferon induction through the MAVS, IKKε, and IRF7 signaling axis during viral infection. J Biol Chem. 2023 Jul;299(7):104925. doi: 10.1016/j.jbc.2023.104925. Epub 2023 Jun 14. PubMed PMID: 37328105.

Baek A, Lee G, Golconda S, Rayhan A, Manganaris A, Chen S, Tirumuru N, Yu H, Kim S, Kimmel C, Zablocki O, Sullivan M, Addepalli B, Wu L, Kim S. Single-RNA-level analysis of full-length HIV-1 RNAs reveals functional redundancy of m6As. Preprint; Under Review at Nature Portfolio. 2023 June. doi: 10.21203/rs.3.rs-2679540/v1.

Jia HH, Chen QY, Jiang ZH, Wang XY, Zhang WJ, He X, Harrison TJ, Jackson JB, Wu L, Fang ZL. A novel subgenotype I3 of hepatitis B virus in Guangxi, China: a 15-year follow-up study. Virus Genes. 2023 Jun;59(3):359-369. doi: 10.1007/s11262-023-01980-6. Epub 2023 Feb 25. PubMed PMID: 36841897.

Yang H, Espada CE, Phillips S, Martinez N, Kenney AD, Yount JS, and Xiong Y, Wu L. The host anti-viral protein SAMHD1 suppresses NF-κB activation by interacting with the IKK complex during inflammatory responses and viral infection. J. Biol. Chem. 2023; 299(6) 104750. PMID: 37100289.

Phillips, S., Mishra, T., Khadka, S., Bohan, D., Espada, C.E., Maury, W. & Wu, L. (2023). Epitranscriptomic N6-Methyladenosine Profile of SARS-CoV-2-Infected Human Lung Epithelial Cells. Microbiol Spectr. 11(1):e0394322. PMID: 36625663doi: 10.1128/spectrum.03943-22.

Phillips S, Baek A, Kim S, Chen S, Wu L. (2022). Protocol for the generation of HIV-1 genomic RNA with altered levels of N6-methyladenosine. STAR Protoc. 3(3):101616. PMID: 35990737. doi: 10.1016/j.xpro.2022.101616

Rojas Chavez RA, Boyt D, Schwery N, Han C, Wu L*, Haim H*. Commonly elicited antibodies against the base of the HIV-1 Env trimer guide the population-level evolution of a structure-regulating region in gp41. J Virol, 2022, Jun 6:e0040622. doi: 10.1128/jvi.00406-22. Epub ahead of print. PMID: 35658529. (* co-corresponding authors).

Lu W, Li TW, Phillips S, Wu L. Reverted HIV-1 Mutants in CD4+ T-Cells Reveal Critical Residues in the Polar Region of Viral Envelope Glycoprotein. Microbiol Spectr. 2021 Dec 22;9(3):e0165321. doi: 10.1128/spectrum.01653-21. Epub 2021 Dec 22. PubMed PMID: 34935422.

Chen QY, Jia HH, Wang XY, Shi YL, Zhang LJ, Hu LP, Wang C, He X, Harrison TJ, Jackson JB, Wu L, Fang ZL. Analysis of entire hepatitis B virus genomes reveals reversion of mutations to wild type in natural infection, a 15 year follow-up study. Infect Genet Evol. 2022 Jan;97:105184. doi: 10.1016/j.meegid.2021.105184. Epub 2021 Dec 11. PubMed PMID: 34902556.

Barrett B, Nguyen DH, Xu J, Guo K, Shetty S, Jones ST, Mickens KL, Shepard C, Roers A, Behrendt R, Wu L, Kim B, Santiago ML. SAMHD1 Promotes the Antiretroviral Adaptive Immune Response in Mice Exposed to Lipopolysaccharide. J Immunol. 2022 Jan 15;208(2):444-453. doi: 10.4049/jimmunol.2001389. Epub 2021 Dec 10. PubMed PMID: 34893529.

Chen S, Kumar S, Espada CE, Tirumuru N, Cahill MP, Hu L, He C, & Wu L. (2021). N6-methyladenosine modification of HIV-1 RNA suppresses type-I interferon induction in differentiated monocytic cells and primary macrophages. PLoS Pathogens, 17(3):e1009421PMID: 33690734.

Espada CE, St. Gelais C, Bonifati S, Maksimova VV, Cahill MP, Kim SH, & Wu L. (2021). TRAF6 and TAK1 contribute to SAMHD1-mediated negative regulation of NF-kB signaling. J Virol, 95(3), e01970-20. PMID: 33177202.

Rojas Chavez RA, Boyt D, Han C, & Wu L, Haim H. The fusion peptide proximal region of the HIV-1 envelope glycoprotein regulates exposure of immunogenic epitopes at the trimer base. 2020. bioRxiv preprint

Qin, Z., Bonifati, S., St Gelais, C., Li, T. W., Kim, S. H., Antonucci, J. M., Mahboubi, B., Yount, J. S., Xiong, Y., Kim, B. & Wu, L. (2020). The dNTPase activity of SAMHD1 is important for its suppression of innate immune responses in differentiated monocytic cells. J Biol Chem, 295(6):1575-1586. PMID: 31914403. 

Lu, W., Chen, S., Yu, J., Behrens, R., Wiggins, J., Sherer, N., Liu, S. L., Xiong, Y., Xiang, S. H. & Wu, L. (2019). The Polar Region of the HIV-1 Envelope Protein Determines Viral Fusion and Infectivity by Stabilizing the gp120-gp41 Association. J Virol, 93(7), e02128-18. PMID: 30651369.

Tirumuru, N., Wu, L. (2019). HIV-1 envelope proteins up-regulate N6-methyladenosine levels of cellular RNA independently of viral replication. J Biol Chem, 294(9), 3249-3260. PMID: 30617182.

Chemudupati, M., Kenney, A. D., Bonifati, S., Zani, A., McMichael, T. M., Wu, L. & Yount, J. S. (2019). From APOBEC to ZAP: Diverse mechanisms used by cellular restriction factors to inhibit virus infections. Biochim Biophys Acta Mol Cell Res, 1866(3), 382-394. PMID: 30290238.

Chen, S., Bonifati, S., Qin, Z., St Gelais, C. & Wu, L. (2019). SAMHD1 Suppression of Antiviral Immune Responses. Trends Microbiol, 27(3), 254-267. PMID: 30336972.

Lu, W., Tirumuru, N., St Gelais, C., Koneru, P. C., Liu, C., Kvaratskhelia, M., He, C. & Wu, L. (2018). N6-Methyladenosine-binding proteins suppress HIV-1 infectivity and viral production. J Biol Chem, 293(34), 12992-13005. PMID: 29976753.

Guo, J., Liu, X., Wu, C., Hu, J., Peng, K., Wu, L., Xiong, S. & Dong, C. (2018). The transmembrane nucleoporin Pom121 ensures efficient HIV-1 pre-integration complex nuclear import. Virology, 521, 169-174. PMID: 29957337.

Antonucci, J. M., Kim, S. H., St Gelais, C., Bonifati, S., Li, T. W., Buzovetsky, O., Knecht, K. M., Duchon, A. A., Xiong, Y., Musier-Forsyth, K. & Wu, L. (2018). SAMHD1 Impairs HIV-1 Gene Expression and Negatively Modulates Reactivation of Viral Latency in CD4+ T Cells. J Virol, 92(15), e00292-18. PMID: 29793958.

Liu, S., Wang, Q., Yu, X., Li, Y., Guo, Y., Liu, Z., Sun, F., Hou, W., Li, C., Wu, L., Guo, D. & Chen, S. (2018). HIV-1 inhibition in cells with CXCR4 mutant genome created by CRISPR-Cas9 and piggyBac recombinant technologies. Sci Rep, 8(1), 8573. PMID: 29872154.

Chen, S., Bonifati, S., Qin, Z., St Gelais, C., Kodigepalli, K. M., Barrett, B. S., Kim, S. H., Antonucci, J. M., Ladner, K. J., Buzovetsky, O., Knecht, K. M., Xiong, Y., Yount, J. S., Guttridge, D. C., Santiago, M. L. & Wu, L. (2018). SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-kB and interferon pathways. Proc Natl Acad Sci U S A, 115(16), E3798-E3807. PMID: 29610295.

St Gelais, C., Kim, S. H., Maksimova, V. V., Buzovetsky, O., Knecht, K. M., Shepard, C., Kim, B., Xiong, Y. & Wu, L. (2018). A Cyclin-Binding Motif in Human SAMHD1 Is Required for Its HIV-1 Restriction, dNTPase Activity, Tetramer Formation, and Efficient Phosphorylation. J Virol, 92(6), e01787-17. PMID: 29321329.

Buzovetsky, O., Tang, C., Knecht, K. M., Antonucci, J. M., Wu, L., Ji, X. & Xiong, Y. (2018). The SAM domain of mouse SAMHD1 is critical for its activation and regulation. Nat Commun, 9(1), 411. PMID: 29379009.

Kodigepalli, K. M., Bonifati, S., Tirumuru, N. & Wu, L. (2018). SAMHD1 modulates in vitro proliferation of acute myeloid leukemia-derived THP-1 cells through the PI3K-Akt-p27 axis. Cell Cycle, 17(9), 1124-1137. PMID: 29911928.

Kodigepalli, K. M., Li, M., Bonifati, S., Panfil, A. R., Green, P. L., Liu, S. L. & Wu, L. (2018). SAMHD1 inhibits epithelial cell transformation in vitro and affects leukemia development in xenograft mice. Cell Cycle, 17(23), 2564-2576. PMID: 30474474.

Kenney, A. D., Dowdle, J. A., Bozzacco, L., McMichael, T. M., St Gelais, C., Panfil, A. R., Sun, Y., Schlesinger, L. S., Anderson, M. Z., Green, P. L., López, C. B., Rosenberg, B. R., Wu, L. & Yount, J. S. (2017). Human Genetic Determinants of Viral Diseases. Annu Rev Genet, 51, 241-263. PMID: 28853921.

Wang, Q., Chen, S., Xiao, Q., Liu, Z., Liu, S., Hou, P., Zhou, L., Hou, W., Ho, W., Li, C., Wu, L. & Guo, D. (2017). Genome modification of CXCR4 by Staphylococcus aureus Cas9 renders cells resistance to HIV-1 infection. Retrovirology, 14(1), 51. PMID: 29141633.

Antonucci, J. M., St Gelais, C. & Wu, L. (2017). The Dynamic Interplay between HIV-1, SAMHD1, and the Innate Antiviral Response. Front Immunol, 8, 1541. PMID: 29176984.

Duchon, A. A., St Gelais, C., Titkemeier, N., Hatterschide, J., Wu, L. & Musier-Forsyth, K. (2017). HIV-1 Exploits a Dynamic Multi-aminoacyl-tRNA Synthetase Complex To Enhance Viral Replication. J Virol, 91(21), e01240-17. PMID: 28814526.

Liu, Z., Chen, S., Jin, X., Wang, Q., Yang, K., Li, C., Xiao, Q., Hou, P., Liu, S., Wu, S., Hou, W., Xiong, Y., Kong, C., Zhao, X., Wu, L., Li, C., Sun, G. & Guo, D. (2017). Genome editing of the HIV co-receptors CCR5 and CXCR4 by CRISPR-Cas9 protects CD4+ T cells from HIV-1 infection. Cell Biosci, 7, 47. PMID: 28904745.

Kodigepalli, K. M., Li, M., Liu, S. L. & Wu, L. (2017). Exogenous expression of SAMHD1 inhibits proliferation and induces apoptosis in cutaneous T-cell lymphoma-derived HuT78 cells. Cell Cycle, 16(2), 179-188. PMID: 27929746.

Kohnken, R., Kodigepalli, K. M., Mishra, A., Porcu, P. & Wu, L. (2017). MicroRNA-181 contributes to downregulation of SAMHD1 expression in CD4+ T-cells derived from Sèzary syndrome patients. Leuk Res, 52, 58-66. PMID: 27889686.

St Gelais, C., Kim, S. H., Ding, L., Yount, J. S., Ivanov, D., Spearman, P. & Wu, L. (2016). A Putative Cyclin-binding Motif in Human SAMHD1 Contributes to Protein Phosphorylation, Localization, and Stability. J Biol Chem, 291(51), 26332-26342. PMID: 27815502.

Li, C., Wang, H. B., Kuang, W. D., Ren, X. X., Song, S. T., Zhu, H. Z., Li, Q., Xu, L. R., Guo, H. J., Wu, L. & Wang, J. H. (2016). Naf1 Regulates HIV-1 Latency by Suppressing Viral Promoter-Driven Gene Expression in Primary CD4+ T Cells. J Virol, 91(1), e01830-16. PMID: 27795436.

Antonucci, J. M., St Gelais, C., de Silva, S., Yount, J. S., Tang, C., Ji, X., Shepard, C., Xiong, Y., Kim, B. & Wu, L. (2016). SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity. (Vols. 22). (10), pp. 1072-1074. Nat Med. PMID: 27711056.

Bonifati, S., Daly, M. B., St Gelais, C., Kim, S. H., Hollenbaugh, J. A., Shepard, C., Kennedy, E. M., Kim, D. H., Schinazi, R. F., Kim, B. & Wu, L. (2016). SAMHD1 controls cell cycle status, apoptosis and HIV-1 infection in monocytic THP-1 cells. Virology, 495, 92-100. PMID: 27183329.

Tirumuru, N., Zhao, B. S., Lu, W., Lu, Z., He, C. & Wu, L. (2016). N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression. Elife, 5, e15528. PMID: 27371828.

Ren, X. X., Wang, H. B., Li, C., Jiang, J. F., Xiong, S. D., Jin, X., Wu, L. & Wang, J. H. (2016). HIV-1 Nef-associated Factor 1 Enhances Viral Production by Interacting with CRM1 to Promote Nuclear Export of Unspliced HIV-1 gag mRNA. J Biol Chem, 291(9), 4580-8. PMID: 26733199.

Wang, F., St Gelais, C., de Silva, S., Zhang, H., Geng, Y., Shepard, C., Kim, B., Yount, J. S. & Wu, L. (2016). Phosphorylation of mouse SAMHD1 regulates its restriction of human immunodeficiency virus type 1 infection, but not murine leukemia virus infection. Virology, 487, 273-84. PMID: 26580513.

Tang, C., Ji, X., Wu, L. & Xiong, Y. (2015). Impaired dNTPase activity of SAMHD1 by phosphomimetic mutation of Thr-592. J Biol Chem, 290(44), 26352-9. PMID: 26294762.

Kohnken, R., Kodigepalli, K. M. & Wu, L. (2015). Regulation of deoxynucleotide metabolism in cancer: novel mechanisms and therapeutic implications. Mol Cancer, 14, 176. PMID: 26416562.

St Gelais, C., Roger, J. & Wu, L. (2015). Non-POU Domain-Containing Octamer-Binding Protein Negatively Regulates HIV-1 Infection in CD4(+) T Cells. AIDS Res Hum Retroviruses, 31(8), 806-16. PMID: 25769457.

Wong, H. K., Wu, L., de Silva, S., Porcu, P. & Mishra, A. (2015). Cutaneous T Cell Lymphoma: Mycosis Fungoides and Sézary Syndrome. In Q. Lu , C. C. Chang , B. C. Richardson (Eds.) Epigenetics and Dermatology. pp. 363-377. Academic Press.

Mates, J. M., de Silva, S., Lustberg, M., Van Deusen, K., Baiocchi, R. A., Wu, L. & Kwiek, J. J. (2015). A Novel Histone Deacetylase Inhibitor, AR-42, Reactivates HIV-1 from Chronically and Latently Infected CD4+ T-cells. Retrovirology (Auckl)., 7, 1-5. PMID: 26855567.

de Silva, S., St Gelais, C., Nagaraja, T. & Wu, L. (2015). Counteraction of SAMHD1 by Vpx. In T. Hope , D. Richman , M. Stevenson (Eds.) Encyclopedia of AIDS. (33), pp. 08. New York, NY: Springer.

Sharma, A., Slaughter, A., Jena, N., Feng, L., Kessl, J. J., Fadel, H. J., Malani, N., Male, F., Wu, L., Poeschla, E., Bushman, F. D., Fuchs, J. R. & Kvaratskhelia, M. (2014). A new class of multimerization selective inhibitors of HIV-1 integrase. PLoS Pathog, 10(5), e1004171. PMID: 24874515.

St Gelais, C., de Silva, S., Hach, J. C., White, T. E., Diaz-Griffero, F., Yount, J. S. & Wu, L. (2014). Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1. J Virol, 88(10), 5834-44. PMID: 24623419.

Ren, X. X., Ma, L., Liu, Q. W., Li, C., Huang, Z., Wu, L., Xiong, S. D., Wang, J. H. & Wang, H. B. (2014). The molecule of DC-SIGN captures enterovirus 71 and confers dendritic cell-mediated viral trans-infection. Virol J, 11, 47. PMID: 24620896.

de Silva, S., Wang, F., Hake, T. S., Porcu, P., Wong, H. K. & Wu, L. (2014). Downregulation of SAMHD1 expression correlates with promoter DNA methylation in Sézary syndrome patients. (Vols. 134). (2), pp. 562-565. J Invest Dermatol. PMID: 23884314.

Wu, L. (2014). East or West, Virology is best: a personal journey. In Y. M. Wen , Z. H. Yuan (Eds.) Progress of Microbe and Infection Research. pp. 108-117. Shanghai: Fudan University Press.

Wu, L. (2013). SAMHD1 knockout mice: modeling retrovirus restriction in vivo. Retrovirology, 10, 142. PMID: 24257155.

Wu, L., Schwartz, O. (Eds.) (2013). HIV Interactions with Dendritic Cells: Infection and Immunity. In Advances in Experimental Medicine and Biology. (Vols. 762). New York, NY: Springer Science + Business Media.

Coleman, C. M., St Gelais, C. & Wu, L. (2013). Cellular and viral mechanisms of HIV-1 transmission mediated by dendritic cells. In L. Wu , O. Schwartz (Eds.) HIV Interactions with Dendritic Cells: Infection and Immunity. pp. 109-130. New York, NY: Springer.

Zhai, R. R., Jiang, A. P., Wang, H. B., Ma, L., Ren, X. X., Jiang, J. F., Wu, L., Wei, J. F. & Wang, J. H. (2013). Histamine enhances HIV-1-induced modulation of dendritic cells to skew naïve T cell differentiation toward regulatory T cells. Virology, 442(2), 163-72. PMID: 23652320.

Sharma, A., Larue, R. C., Plumb, M. R., Malani, N., Male, F., Slaughter, A., Kessl, J. J., Shkriabai, N., Coward, E., Aiyer, S. S., Green, P. L., Wu, L., Roth, M. J., Bushman, F. D. & Kvaratskhelia, M. (2013). BET proteins promote efficient murine leukemia virus integration at transcription start sites. Proc Natl Acad Sci U S A, 110(29), 12036-41. PMID: 23818621.

Wu, L. (2013). Cellular and Biochemical Mechanisms of the Retroviral Restriction Factor SAMHD1. ISRN Biochem, 2013. PMID: 24523981.

Barrios, C. S., Castillo, L., Giam, C. Z., Wu, L. & Beilke, M. A. (2013). Inhibition of HIV type 1 replication by human T lymphotropic virus types 1 and 2 Tax proteins in vitro. AIDS Res Hum Retroviruses, 29(7), 1061-7. PMID: 23464580.

Dong, C., Zhao, G., Zhong, M., Yue, Y., Wu, L. & Xiong, S. (2013). RNA sequencing and transcriptomal analysis of human monocyte to macrophage differentiation. Gene, 519(2), 279-87. PMID: 23458880.

de Silva, S., Hoy, H., Hake, T. S., Wong, H. K., Porcu, P. & Wu, L. (2013). Promoter methylation regulates SAMHD1 gene expression in human CD4+ T cells. J Biol Chem, 288(13), 9284-92. PMID: 23426363.

St Gelais, C., de Silva, S., Amie, S. M., Coleman, C. M., Hoy, H., Hollenbaugh, J. A., Kim, B. & Wu, L. (2012). SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+ T-lymphocytes cannot be upregulated by interferons. Retrovirology, 9, 105. PMID: 23231760.

Coon, S., Wang, D. & Wu, L. (2012). Polymorphisms of the SAMHD1 gene are not associated with the infection and natural control of HIV type 1 in Europeans and African-Americans. AIDS Res Hum Retroviruses, 28(12), 1565-73. PMID: 22530776.

Wu, L. (2012). SAMHD1: a new contributor to HIV-1 restriction in resting CD4+ T-cells. Retrovirology, 9, 88. PMID: 23092163.

Kessl, J. J., Jena, N., Koh, Y., Taskent-Sezgin, H., Slaughter, A., Feng, L., de Silva, S., Wu, L., Le Grice, S. F., Engelman, A., Fuchs, J. R. & Kvaratskhelia, M. (2012). Multimode, cooperative mechanism of action of allosteric HIV-1 integrase inhibitors. J Biol Chem, 287(20), 16801-11. PMID: 22437836.

St Gelais, C., Coleman, C. M., Wang, J. H. & Wu, L. (2012). HIV-1 Nef enhances dendritic cell-mediated viral transmission to CD4+ T cells and promotes T-cell activation. PLoS One, 7(3), e34521. PMID: 22479639.

de Silva, S., Planelles, V. & Wu, L. (2012). Differential effects of Vpr on single-cycle and spreading HIV-1 infections in CD4+ T-cells and dendritic cells. PLoS One, 7(5), e35385. PMID: 22570689.

Zhang, C., de Silva, S., Wang, J. H. & Wu, L. (2012). Co-evolution of primate SAMHD1 and lentivirus Vpx leads to the loss of the vpx gene in HIV-1 ancestor. PLoS One, 7(5), e37477. PMID: 22574228.

Wu, L. (2011). The role of monocyte-lineage cells in human immunodeficiency virus persistence: mechanisms and progress. Wei Sheng Wu Yu Gan Ran, 6(3), 129-132. PMID: 22091217.

Zhu, Y., Chen, G., Lv, F., Wang, X., Ji, X., Xu, Y., Sun, J., Wu, L., Zheng, Y. T. & Gao, G. (2011). Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation. Proc Natl Acad Sci U S A, 108(38), 15834-9. PMID: 21876179.

St Gelais, C., Wu, L. (2011). SAMHD1: a new insight into HIV-1 restriction in myeloid cells. Retrovirology, 8, 55. PMID: 21740548.

de Silva, S., Wu, L. (2011). TRIM5 acts as more than a retroviral restriction factor. Viruses, 3(7), 1204-9. PMID: 21866272.

Coleman, C. M., Spearman, P. & Wu, L. (2011). Tetherin does not significantly restrict dendritic cell-mediated HIV-1 transmission and its expression is upregulated by newly synthesized HIV-1 Nef. Retrovirology, 8, 26. PMID: 21504576.

Qin, Y., Li, Y., Liu, W., Tian, R., Guo, Q., Li, S., Li, H., Zhang, D., Zheng, Y., Wu, L., Lan, K. & Wang, J. (2011). Penicillium marneffei-stimulated dendritic cells enhance HIV-1 trans-infection and promote viral infection by activating primary CD4+ T cells. PLoS One, 6(11), e27609. PMID: 22110688.

Raghavendra, N. K., Shkriabai, N., Graham, R. L., Hess, S., Kvaratskhelia, M. & Wu, L. (2010). Identification of host proteins associated with HIV-1 preintegration complexes isolated from infected CD4+ cells. Retrovirology, 7, 66. PMID: 20698996.

Blanchet, F. P., Moris, A., Nikolic, D. S., Lehmann, M., Cardinaud, S., Stalder, R., Garcia, E., Dinkins, C., Leuba, F., Wu, L., Schwartz, O., Deretic, V. & Piguet, V. (2010). Human immunodeficiency virus-1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responses. Immunity, 32(5), 654-69. PMID: 20451412.

Chung, N. P., Breun, S. K., Bashirova, A., Baumann, J. G., Martin, T. D., Karamchandani, J. M., Rausch, J. W., Le Grice, S. F., Wu, L., Carrington, M. & Kewalramani, V. N. (2010). HIV-1 transmission by dendritic cell-specific ICAM-3-grabbing nonintegrin (DC-SIGN) is regulated by determinants in the carbohydrate recognition domain that are absent in liver/lymph node-SIGN (L-SIGN). J Biol Chem, 285(3), 2100-12. PMID: 19833723.

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Wang, J. H., Wells, C. & Wu, L. (2008). Macropinocytosis and cytoskeleton contribute to dendritic cell-mediated HIV-1 transmission to CD4+ T cells. Virology, 381(1), 143-54. PMID: 18804253.

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